October 1 - 3,  2008      Rotterdam      The Netherlands

2008

Programme

Wednesday       October 1, 2008

11.30                      REGISTRATION

13.30  Welcome

           Jan Trapman (Erasmus MC, Rotterdam, The Netherlands)

                       Session 1: Novel Technologies

13.45  Keynote speaker

           Michael Mancini (Baylor College of Medicine, Houston, USA)

                  Intranuclear dynamics of nuclear receptors and cofactors

14.20  René Houtman (Pamgene, ‘s Hertogenbosch, The Netherlands)

                  Interaction of nuclear receptors with peptide motifs

14.40  Ian Mills (University of Cambridge, UK)

                  Androgen target genes

15.00  Speaker selected from abstracts

15.15 – 15.45          BREAK + POSTER VIEWING

15.45  Fahri Saatcioglu (University of Oslo, Norway)

                  Ligand-specific dynamics of the androgen receptor in living cells

16.05  Cor Kuil (Organon-Schering Plough, Oss, The Netherlands)

                  Drug development on steroid hormone receptors

16.25  Speaker selected from abstracts

16.40  Keynote speaker

           Gordon Hager (NIH,Bethesda, USA)

                  Subnuclear trafficking and gene targeting by steroid receptors

17.15                        FINISH

18.00 – 19.30          RECEPTION

Thursday       October 2, 2008, morning programme

                       Session 2: Transcriptional Control by Androgen Receptors I

09.00  Keynote speaker

           Wouter de Laat (Erasmus MC, Rotterdam, The Netherlands)

                   Inter-chromosomal gene regulation in the
                   mammalian cell nucleus

09.35  Frank Claessens (University of Leuven, Belgium)

                   The hinge region of the androgen receptor

09.55  Roland Schüle (Klinikum der Universität Freiburg, Germany)

                   Androgen action and histone modifications

10.15  Speaker selected from abstracts

10.30 – 11.00          BREAK + POSTER VIEWING

11.00  Bernard Haendler (Bayer-Schering Pharma AG,Berlin, Germany)

                  Functional consequences of AR acetylation

11.20  Craig Robson (University of Newcastle upon Tyne, UK)

                  Properties and expression of AR coregulators

11.40  Speaker selected from abstracts

11.55 – 14.30          LUNCH + POSTER SESSION

Thursday       October 2, 2008, afternoon programme

                       Session 3: Transcriptional Control by Androgen Receptors II

14.30  Keynote speaker

           Marc Timmers (UMC, Utrecht, The Netherlands)

                   Dynamic regulation of core promoter activity

15.05  Olli Jänne (University of Helsinki, Finland)

                 Structural and functional analysis of androgen receptor
                 on chromatin

15.25  Guido Jenster (Erasmus MC, Rotterdam, The Netherlands)

                   Gene expression profiling of the human prostate zones

15.45  Speaker selected from abstracts

16.00 – 16.30          BREAK + POSTER VIEWING

16.30  Charlotte Bevan (Imperial College, London, UK)

                  Mechanisms of androgen receptor repression

16.50  Speaker selected from abstracts

17.05  Keynote speaker

           Bas van Steensel (NKI, Amsterdam, The Netherlands)

                   Genome-wide views of chromatin structure and function

17.40                        POSTER AWARD CEREMONY

17.50                        FINISH

20.00                        CONGRESS DINNER

Friday       October 3, 2008

                       Session 4: Molecular Basis of Prostate Cancer

09.00  Keynote speaker

           Fritz Schröder (Erasmus MC, Rotterdam, The Netherlands)

                  Early detection of prostate cancer in 2008

09.35  Keynote speaker

           Steven Balk (Harvard Medical School, Boston, USA)

                  AR, the cell cycle and prostate cancer

10.10  Norman Maitland (University of York, UK)

                  Prostate cancer stem cells

10.30  Speaker selected from abstracts

10.45 – 11.15          BREAK

11.15  Ralf Hoffmann (Philips Research, Eindhoven, The Netherlands)

                  Phosphodiesterases in prostate cancer

11.35  Frank de Jong (Erasmus MC, Rotterdam, The Netherlands)

                  Intraprostatic androgens and expression of androgen
                  biosynthetic enzymes

11.55  Colin Cooper (Institute of Cancer Research, Sutton, UK)

                  Fusion transcripts in prostate cancer

12.15  Speaker selected from abstracts

12.30  Keynote speaker

           James Dalton (GTx, Inc, Memphis, USA)

                Structure-based design of selective androgen receptor modulators

13.05                        CLOSURE

Contact: m.a.vandenakker@erasmusmc.nl