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Session 1: Novel Technologies

13.45 Keynote speaker

Michael Mancini (Baylor College of Medicine, Houston, USA)

Nuclear receptor functional analysis by high throughput
systems biology

14.20 René Houtman (Pamgene, ‘s Hertogenbosch, The Netherlands)

MARCoNI: receiving the signals of nuclear receptor-coregulator
interactions

14.40 Ian Mills (University of Cambridge, UK)

Androgen target genes

15.00 Martin van Royen (Erasmus MC, Rotterdam, The Netherlands)

A two-step model for androgen receptor domain interactions
in living cells

15.45 Fahri Saatcioglu (University of Oslo, Norway)

Ligand-specific dynamics of the androgen receptor at its
response elements in living cells

16.05 Cor Kuil (Organon-Schering Plough, Oss, The Netherlands)

Drug discovery on steroid hormone receptors

16.25 Nicola Clegg (Memorial Sloan Kettering Cancer Center, New York, USA)

Development of androgen receptor antagonists with
a novel mechanism of action

16.40 Keynote speaker

Gordon Hager (NIH,Bethesda, USA)

Genome wide nuclear receptor/chromatin interactions

Session 2: Transcriptional Control by Androgen Receptors I

09.00 Keynote speaker

Wouter de Laat (Erasmus MC, Rotterdam, The Netherlands)

Inter-chromosomal gene regulation in the
mammalian cell nucleus

09.35 Frank Claessens (University of Leuven, Belgium)

The colorful world of androgen response elements

09.55 Roland Schüle (Klinikum der Universität Freiburg, Germany)

Androgen action and histone modifications in prostate cancer

10.15 Nan Wang (University of Newcastle upon Tyne, UK)

Functional characterization of histone methyltransferase
SET9 in prostate cancer cells

11.00 Bernard Haendler (Bayer-Schering Pharma AG,Berlin, Germany)

Functional consequences of androgen receptor acetylation

11.20 Craig Robson (University of Newcastle upon Tyne, UK)

Properties and expression of AR coregulators

11.40 Hannelore Heemers (Mayo Clinic, Rochester, MN, USA)

Coregulators in prostate cancer: regulating the regulators

Session 3: Transcriptional Control by Androgen Receptors II

14.30 Keynote speaker

Marc Timmers (UMC, Utrecht, The Netherlands)

Dynamic regulation of core promoter activity

15.05 Olli Jänne (University of Helsinki, Finland)

Structural and functional analysis of androgen receptor
on chromatin

15.25 Guido Jenster (Erasmus MC, Rotterdam, The Netherlands)

Gene expression profiling of the human prostate zones

15.45 Axel Thomson (MRC, Edinburgh, UK)

Androgens, Notch signaling and stromal survival
during prostate development

16.30 Charlotte Bevan (Imperial College, London, UK)

Mechanisms of androgen receptor repression

16.50 Jorma Palvimo (University of Kuopio, Finland)

Androgens regulate ETS-like transcription factor 4
in prostate cancer cells

17.05 Keynote speaker

Bas van Steensel (NKI, Amsterdam, The Netherlands)

Genome-wide views of chromatin structure and function

Session 4: Molecular Basis of Prostate Cancer

09.00 Keynote speaker

Fritz Schröder (Erasmus MC, Rotterdam, The Netherlands)

Early detection of prostate cancer in 2008

09.35 Keynote speaker

Steven Balk (Harvard Medical School, Boston, USA)

AR, the cell cycle and prostate cancer

10.10 Frank de Jong (Erasmus MC, Rotterdam, The Netherlands)

Intraprostatic androgens and expression of androgen
biosynthetic enzymes

10.30 Elahe Mostaghel (Fred Hutchinson Cancer Research Center,
Seattle, USA)

Androgen levels and steroidogenic enzyme expression in
castration resistant prostate cancer metastases

11.15 Ralf Hoffmann (Philips Research, Eindhoven, The Netherlands)

Phosphodiesterases in prostate cancer

11.35 Norman Maitland (University of York, UK)

The challenge of targeting stem cells in prostate cancer

11.55 Colin Cooper (Institute of Cancer Research, Sutton, UK)

Fusion transcripts in prostate cancer

12.15 Delila Gasi (Erasmus MC, Rotterdam, The Netherlands)

A small region on chromosome 14 is a hot-spot for ETV1
rearrangements in prostate cancer

12.30 Keynote speaker

James Dalton (GTx, Inc, Memphis, USA)

Pharmacology of Selective Androgen Receptor
Modulators (SARMs)